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Repetitive nerve stimu-lation (RNS) studies of the peripheral nerve are widelyavailable and demonstrate significant decrements in theCMAP amplitude in myasthenics, but have a sensitivityof 60–70%. The specialized functions of this high-affinity Treg IL-2R have been covered in the previous chapters as well as just recently when discussing Tregfunction during a inflammatory response where their use of IL-2 shuts-down anergy via theinduction of low-level translation of the cAMP/PKC pathway (Becker 1987).
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